Section
Guides
4 pages in this section, most recently updated September 4, 2026. Each opens with a plain-English summary and cites its sources.
01 · Guides
FeaturedHow the GLP-1 class works: one receptor, then two, then three
You'll get: GLP-1 is a gut hormone that raises insulin when sugar is high, slows the stomach, and lowers appetite.
The biology behind every GLP-1 drug: what the hormone does, why it had to be rebuilt to last, what GIP, glucagon and amylin add, how the new pill differs.
Updated September 4, 202602 · Guides
FeaturedApproved, investigational, discontinued, compounded: what each status means
You'll get: Approved means the FDA reviewed one product for set uses; it does not mean approved for every use.
What approved, discontinued, investigational and compounded mean for GLP-1 drugs, and why compounded semaglutide and tirzepatide sit outside FDA approval.
Updated September 4, 202603 · Guides
FeaturedGLP-1 approval timeline, 2005 to 2026
You'll get: This page lists every FDA approval for GLP-1 drugs in date order, from Byetta in 2005 to Mounjaro's heart indication in 2026.
Every FDA approval for GLP-1 drugs in date order, from Byetta in 2005 to Mounjaro's heart indication in August 2026, each with its FDA application number.
Updated September 4, 202604 · Guides
Glossary: the terms used on every GLP-1 entry
You'll get: This page defines the words used across the site, from GLP-1 and GIP to boxed warning and compounded.
Plain definitions of the terms used on every GLP-1 entry: the hormones, the drug types, label words like boxed warning, FDA terms, and trial vocabulary.
Updated September 4, 2026